Recovery
GHK-Cu
GHK-Cu (Glycyl-L-Histidyl-L-Lysine:Copper 2+) is a naturally occurring copper-binding tripeptide with pleiotropic biological effects. Research demonstrates activation of over 4,000 human genes, including those governing wound healing, anti-inflammatory responses, antioxidant defense, and collagen synthesis. It functions as a tissue remodeling signal, reversing gene expression patterns associated with aging. Its role as a copper chaperone in superoxide dismutase function adds a distinct antioxidant research dimension.
Mechanism of Action
Activates tissue remodeling gene programs; promotes collagen, elastin, and glycosaminoglycan synthesis; functions as copper chaperone for Cu/Zn-SOD antioxidant enzyme; suppresses TGF-β fibrotic signaling.
Research Applications
- → Skin aging and wound healing research
- → Hair follicle stimulation models
- → Pulmonary fibrosis gene expression studies
- → Antioxidant and anti-inflammatory investigations
Analytical Validation
HPLC purity ≥ 98.5%; copper content confirmed by ICP-MS; molecular weight 340.4 Da verified; endotoxin < 1 EU/mg.
For research use only